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  1. Research

    Interplay of digital and analog control in time-resolved gene expression profiles

    Measuring the agreement between a gene expression profile and a known transcriptional regulatory network is an important step in the functional interpretation of bacterial physiological state. In this way, gen...

    Moritz E. Beber, Patrick Sobetzko, Georgi Muskhelishvili and Marc-Thorsten Hütt

    EPJ Nonlinear Biomedical Physics 2016 4:8

    Published on: 22 August 2016

  2. Review

    The Physics behind Systems Biology

    Systems Biology is a young and rapidly evolving research field, which combines experimental techniques and mathematical modeling in order to achieve a mechanistic understanding of processes underlying the regu...

    Nicole E. Radde and Marc-Thorsten Hütt

    EPJ Nonlinear Biomedical Physics 2016 4:7

    Published on: 12 August 2016

  3. Research

    Real-time brain computer interface using imaginary movements

    Brain Computer Interface (BCI) is the method of transforming mental thoughts and imagination into actions. A real-time BCI system can improve the quality of life of patients with severe neuromuscular disorders...

    Ahmad El-Madani, Helge BD Sorensen, Troels W. Kjær, Carsten E. Thomsen and Sadasivan Puthusserypady

    EPJ Nonlinear Biomedical Physics 2015 3:9

    Published on: 28 October 2015

  4. Research

    Does changing Fitts’ index of difficulty evoke transitions in movement dynamics?

    The inverse relationship between movement speed and accuracy in goal-directed aiming is mostly investigated using the classic Fitts’ paradigm. According to Fitts’ law, movement time scales linearly with a sing...

    Raoul Huys, Hester Knol, Rita Sleimen-Malkoun, Jean-Jacques Temprado and Viktor K. Jirsa

    EPJ Nonlinear Biomedical Physics 2015 3:8

    Published on: 12 August 2015

  5. Debate

    Genius and nonlinear dynamics

    Genius is defined as a person of outstanding mental skills. These skills result from genius’ brain structure and physiology that are determined by genetics. It seems that environment and education may only inh...

    Wlodzimierz Klonowski

    EPJ Nonlinear Biomedical Physics 2015 3:7

    Published on: 12 August 2015

  6. Research

    Optimization of combination chemotherapy based on the calculation of network entropy for protein-protein interactions in breast cancer cell lines

    In this report, we show how entropy computation can be applied to the characterization of a protein-protein interaction networks to assist the selection of personalized chemotherapeutic strategy for cancer tre...

    Nicolas Carels, Tatiana Martins Tilli and Jack A. Tuszynski

    EPJ Nonlinear Biomedical Physics 2015 3:6

    Published on: 11 August 2015

  7. Research

    Brain connectivity extended and expanded

    The article is focused on the brain connectivity extensions and expansions, with the introductory elements in this section.

    Obrad Kasum, Edin Dolicanin, Aleksandar Perovic and Aleksandar Jovanovic

    EPJ Nonlinear Biomedical Physics 2015 3:4

    Published on: 10 April 2015

  8. Review

    Application of texture analysis to muscle MRI: 2 – technical recommendations

    A goal of the multicenter European Cooperation in Science and Technology (COST) action MYO-MRI is to optimize Magnetic Resonance Imaging Texture Analysis (MRI-TA) methods for application in the study of muscle...

    Richard A Lerski, Jacques D de Certaines, Dorota Duda, Wlodzimierz Klonowski, Guanyu Yang, Jean Louis Coatrieux, Noura Azzabou and Pierre-Antoine Eliat

    EPJ Nonlinear Biomedical Physics 2015 3:2

    Published on: 19 March 2015

  9. Review

    Application of texture analysis to muscle MRI: 1-What kind of information should be expected from texture analysis?

    Several previous clinical or preclinical studies using computerized texture analysis of MR Images have demonstrated much more clinical discrimination than visual image analysis by the radiologist. In muscular ...

    Jacques D De Certaines, Thibaut Larcher, Dorota Duda, Noura Azzabou, Pierre-Antoine Eliat, Luis M Escudero, Antonio MG Pinheiro, Guanyu Yang, Jean-Louis Coatrieux, Eduard Snezkho, Alexey Shukelovich, Manuela Pereira and Richard A Lerski

    EPJ Nonlinear Biomedical Physics 2015 3:3

    Published on: 19 March 2015

  10. Research

    Nonlinear analysis of EEG in chess players

    The chess game is a good example of cognitive task which needs a lot of training and experience. The aim of this work is to compare applicability of two nonlinear methods - Higuchi Fractal Dimension and Empiri...

    Pawel Stepien, Wlodzimierz Klonowski and Nikolay Suvorov

    EPJ Nonlinear Biomedical Physics 2015 3:1

    Published on: 12 March 2015

  11. Research

    Intrinsic synergistic-topological mechanism versus synergistic-topological matrix in microtubule self-organization

    In this body of work we investigate the synergistic-topological relationship during self-organization of the microtubule fiber in vitro, which is composed of straight, axially shifted and non-shifted, acentrosoma...

    Vlado A Buljan, R M Damian Holsinger, Brett D Hambly, Vangelis Kanellis, Elie Matar, Xanthe Larkin, Guo Jun Liu, John J Bohorquez-Florez and Richard B Banati

    EPJ Nonlinear Biomedical Physics 2014 2:15

    Published on: 4 December 2014

  12. Research

    A multi-compartment pharmacokinetic model of the interaction between paclitaxel and doxorubicin

    In this paper the interactions between paclitaxel, doxorubicin and the metabolic enzyme CYP3A4 are studied using computational models. The obtained results are compared with those of available clinical data se...

    Kenneth JE Vos, Angela G Martin, Maxine G Trimboli, Lindsay Forestell, Khaled Barakat and Jack A Tuszynski

    EPJ Nonlinear Biomedical Physics 2014 2:13

    Published on: 5 November 2014

  13. Research

    Realistic human muscle pressure for driving a mechanical lung

    An important issue in noninvasive mechanical ventilation consists in understanding the origins of patient-ventilator asynchrony for reducing their incidence by adjusting ventilator settings to the intrinsic ve...

    Emeline Fresnel, Jean-François Muir and Christophe Letellier

    EPJ Nonlinear Biomedical Physics 2014 2:7

    Published on: 19 August 2014

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