Example of mesial temporal lobe seizure recorded during SEEG recording (c) and corresponding SEEG scheme (a) showing the electrodes exploring the temporal lobe structures. A: electrode exploring the amygdala (AMY, medial contacts) and the anterior part of the middle temporal gyrus (MTGa) (lateral contacts) B: electrode exploring the anterior hippocampus (HIPa, medial contacts) and the mid part of MTGm (lateral contacts); TB: Electrode exploring the entorhinal cortex (EC, medial contacts) and the anterior part of the inferior temporal gyrus (ITG, lateral contacts); C: electrode exploring the posterior hippocampus (HIPp, medial contacts) and the posterior part of MTG (MTGp, lateral leads); T: electrode exploring the insular cortex (INS, medial contacts) and the anterior part of the superior temporal gyrus (STG, lateral contacts) F: electrode exploring the frontal lobe (fronto-orbital region FO and superior frontal gyrus SFG). In (b) figure shows the electrodes B (reaching the hippocampus) and A (reaching the amygdala) trajectories in the MRI. c) SEEG traces are represented in bipolar montages. Each line represents the recording between two adjacent contacts. Seizure start from mesial structures, i.e. medial contacts of electrodes A (amygdla), B (Hippocampus), TP (temporal pole) and TB (entorhinal cortex). One can notice the involvement of several structures including neocortical regions during seizure propagation, approximately 30 seconds after the onset.