Fig. 8
From: Reduction of calcium release site models via optimized state aggregation
Effects of luminal regulation calculated from release sites composed of 10 luminal regulated Ca2+ channels. Results from the full release site model and reduced model are shown by lines and empty circles (and crosses in B), respectively. The filled circles show corresponding results from the release site composed of 10 two-state Ca2+ activated channels without luminal regulation. a steady state ER/SR [ Ca2+] as a function of K C . b steady state open probability (dashed line) and the fraction of open channels (solid line) as a function of K C . c spark scores as a function of K C . d spark durations as a function of K C