Fig. 2From: Reduction of calcium release site models via optimized state aggregationState space of a three-state single channel model and a minimal release site model. a The tuple representation of the three-state single channel model in Eq. 15. States C, O, R are represented by (100),(010),(001) respectively. b The topology and connectivity of a release site composed of two three-state channels in the tuple representation. The 6 states CC, CO, CR, OO, OR, RR are represented by (200),(110),(101),(020),(011),(002) respectively. The ranks of the states are labeled in circles. Dashed line boxes and grey boxes represent two sample three-partitions of the two-channel release site \(\mathcal {I}_{1}\) and \(\mathcal {I}_{2}\) in the main textBack to article page