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Table 9 The PK parameters for Equation11modeling doxorubicin for Gianni et al. [[27]] with paclitaxel present

From: A multi-compartment pharmacokinetic model of the interaction between paclitaxel and doxorubicin

j,k K D O X,j,k
1,2 8.14 1 0.0254 X DOX , 2 2.59 1 + 0.319 X DOX , 2 1.59 1 + 1.70 X PTX , 1 1 + 0.000323 X PTX , 1 + 0.233 X PTX , 2 1 + 0.00193 X PTX , 2
1,3 3.08 1 + 3.12 X DOX , 3 0.97 1 + 1.45 X DOX , 3 0.97
1,4 0.359 1 + 0.0001 X DOX , 1 1.55 1 + 0.277 X DOX , 4 1.63 1 + 0.0282 X DOX , 4 0.25
2,0 0.264 1 0.314 X PTX , 2 1 + 0.0119 X PTX , 2
2,1 0.135 1 + 13.9 X DOX , 1 0.87 1 + 0.167 X DOX , 1 0.66 1 + 3.08 X PTX , 1 1 + 0.0441 X PTX , 1 0.0003 X PTX , 2 1 + 0.0078 X PTX , 2
3,1 0.0325 1 + 2.02 X DOX , 1 1.74 1 + 0.143 X DOX , 1 0.61
4,1 0.0046 1 + 7.92 X DOX , 1 1.04 1 + 0.243 X DOX , 1 1.95