Patient airflow (A) and simulated curve (B). Case of a 62 years old male. (BMI =50.2 kg.m −1) with a COPD, ventilated with a VPAP III ventilator (ResMed) in a pressure support mode. Pressure values: P
=30 cmH 2O and P
=6 cmH 2O. These values were also used with the mechanical lung. We set P0.1=4, R=25 cmH 2O/l/s, and C=50 ml/cmH 2O, as commonly used for an obstructive patient (the actual values were not measured).