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Table 1 Parameter values of the model

From: Modeling domain formation of MARCKS and protein kinase C at cellular membranes

Molecule Parameter Value Meaning Ref.
MARCKS     
  [M R K] 7.5 μ M Concentration [4]
  [M R K] o 15 μ M Coverage [29, 30]
  k b mrk 4 ×103 s -1 Binding [23]
  k u mrk 0.1 s -1 Unbinding [23]
  k pkc mrk 0.25 μ M -1 s -1 Phosphorylation [23]
  k mrk 0.15 μ M Michaelis-Menten binding [15]
  k ppa mrk 0.03 s -1 Dephosphorylation [9]
  D c 5 μ m 2 s -1 Cytoplasmic Diffusion [42, 45]
  D m 0.1 μ m 2 s -1 Membrane Diffusion [47]
PKC     
  [P K C] 0.5 μ M Concentration [49]
  k b pkc 140 s -1 Binding [23]
  k u pkc 1 s -1 Unbinding [23]
  k Ca 0.4 μ M Michaelis-Menten Ca2+ [23]
  D c 5 μ m 2 s -1 Cytoplasmic Diffusion [44]
  D m 0.1 μ m 2 s -1 Membrane Diffusion [47]
Ca2+     
  τ 8 s Relaxation time [23]
  [C a 2+] o 0.1 μ M Rest concentration [48]