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Figure 6 | EPJ Nonlinear Biomedical Physics

Figure 6

From: Modeling domain formation of MARCKS and protein kinase C at cellular membranes

Figure 6

Two-dimensional numerical simulations of Eqs. (5-6)in a circular domain. Whereas from an initial asymmetric inhomogeneous distribution of MARCKS and PKC, domains of high protein concentration appear at the membrane (a-b), from an initial homogeneous distribution of MARCKS and PKC with a weak random perturbation, no pattern formation is obtained (c-d). a) and c) Spatio-temporal plot of the concentration of PKC and MARCKS at the membrane. b) and d) Spatial distribution of MARCKS and PKC at the membrane at four different times. Total concentration of the proteins are: [M R K]=10.5 μ M and [P K C]=2.5 μ M.

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