Fig. 1

Local sensitivity analysis of a simple reversible reaction. Top: Model trajectories for model versions A (left), B (center) and C (right) and parameters k ₂=1,x ₀=0.2,k ₁ as indicated. Bottom: Respective normalized local sensitivity coefficients, obtained with parameters \(k_1=1, k_{1}^B = 5\) and \(k_{1}^C = 5\)