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EPJ Nonlinear Biomedical Physics
Fig. 4 | EPJ Nonlinear Biomedical Physics

Fig. 4

From: Optimization of combination chemotherapy based on the calculation of network entropy for protein-protein interactions in breast cancer cell lines

Fig. 4

Expected benefit of top-5 most connected protein of up-regulated genes for 5-year of patient survival. (□): observed data (r = −0.869); (●): expected patient benefit derived from y = −0.0005*x + 11.4732, where y is the entropy of top-5 protein hubs and x is the 5-year survival benefit expected from target inactivation (see Additional file 2: Table S2) by the corresponding specific drug

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