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Table 7 The PK parameters for Equation 11 modeling paclitaxel

From: A multi-compartment pharmacokinetic model of the interaction between paclitaxel and doxorubicin

j,k A P T X,j,k B P T X,j,k Γ P T X,j,k K P T X,j,k
1,2 1.06 1.79 0.0001 13.8 1 + 0.0117 X PTX , 2 1.05 1 + 3.37 X PTX , 2 0.96
1,3 1.40 1.62 0.0000 29.1 1 0.0002 X PTX , 1 1.68 1 + 0.0004 X PTX , 3 1.24 1 + 0.551 X PTX , 3 1.22
1,4 1.23 1.10 0.0000 2.85 1 + 0.0082 X PTX , 4 1.01 1 + 0.117 X PTX , 4 1.22
2,0 1.03 1.99 0.0876 2.98 1 0.0023 X PTX , 2 2.09
2,1 0.94 1.09 0.0028 0.0523 1 0.0023 X PTX , 1 0.97 1 + 0.0015 X PTX , 1 1.32
3,1 1.66 1.93 0.00003 0.0230 1 + 0.0423 X PTX , 1 1.75 1 + 0.0199 X PTX , 1 1.60
4,1 1.78 1.83 0.0009 0.0061 1 0.0054 X PTX , 1 0.89 1 + 6.36 X PTX , 1 0.74