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Table 6 The PK parameters for Equation11modeling doxorubicinol for Moreira et al. [[28]]

From: A multi-compartment pharmacokinetic model of the interaction between paclitaxel and doxorubicin

j,k A D O L,j,k B D O L,j,k Γ DOL,j,k K D O L,j,k
1,2 1.57 2.51 0.3261 15.9 1 + 14.0 X DOL , 2 0.50 1 + 8.04 X DOL , 2 1.24
1,3 1.20 1.00 0.0000 4.82 1 + 0.0749 X DOL , 1 0.95 1 + 0.711 X DOL , 3 1.22 1 + 0.0433 X DOL , 3 1.26
2,0 0.66 2.36 1.3731 13.8 1 0.0162 X DOL , 2 2.07
2,1 0.61 2.02 4.5141 5.03 1 + 0.0690 X DOL , 2 1.11 1 + 0.135 X DOL , 1 0.91 1 + 2.61 X DOL , 1 1.37
3,1 0.60 1.00 0.0000 0.0479 1 + 0.0047 X DOL , 3 1.10 1 7.87 X DOL , 1 1.45 1 + 2.33 X DOL , 1 1.22