Skip to main content

Table 4 The PK parameters for Equation11modeling doxorubicinol for Gianni et al. [[27]]

From: A multi-compartment pharmacokinetic model of the interaction between paclitaxel and doxorubicin

j,k A D O L,j,k B D O L,j,k Γ D O L,j,k K D O L,j,k
1,2 1.76 2.43 0.3371 14.0 1 + 10.6 X DOL , 2 0.72 1 + 4.54 X DOL , 2 1.92
1,3 1.07 1.00 0.0000 3.92 1 + 0.1150 X DOL , 1 0.55 1 + 1.02 X DOL , 3 1.52 1 + 0.0482 X DOL , 3 2.43
2,0 0.72 1.83 1.5722 8.58 1 0.0167 X DOL , 2 1.55
2,1 0.91 1.34 6.8599 3.90 1 + 0.0646 X DOL , 2 1.18 1 + 0.1282 X DOL , 1 0.95 1 + 3.97 X DOL , 1 1.07
3,1 0.79 1.00 0.0000 0.0594 1 + 0.0073 X DOL , 3 2.26 1 6.94 X DOL , 1 1.17 1 + 3.19 X DOL , 1 0.96