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Table 3 The PK parameters for Equation11modeling doxorubicin for Gianni et al. [[27]]

From: A multi-compartment pharmacokinetic model of the interaction between paclitaxel and doxorubicin

j,k A D O X,j,k B D O X,j,k Γ D O X,j,k K D O X,j,k
1,2 0.79 2.52 0.0006 8.14 1 0.0254 X DOX , 2 2.59 1 + 0.319 X DOX , 2 1.59
1,3 0.83 2.43 0.0039 3.08 1 + 3.12 X DOX , 3 0.97 1 + 1.44 X DOX , 3 0.97
1,4 1.59 1.62 0.0012 0.359 1 + 0.0001 X DOX , 1 1.55 1 + 0.277 X DOX , 4 1.63 1 + 0.0282 X DOX , 4 0.25
2,0 1.33 1.00 0.0000 0.264
2,1 1.01 0.53 0.0994 0.135 1 + 13.9 X DOX , 1 0.87 1 + 0.1672 X DOX , 1 0.66
3,1 1.04 1.12 0.0287 0.0325 1 + 2.02 X DOX , 1 1.74 1 + 0.143 X DOX , 1 0.61
4,1 1.79 1.00 0.0000 0.0046 1 + 7.92 X DOX , 1 1.04 1 + 0.243 X DOX , 1 1.95