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Table 2 The PK parameters for Equation 11 modeling doxorubicinol

From: A multi-compartment pharmacokinetic model of the interaction between paclitaxel and doxorubicin

j,k A D O L,j,k B D O L,j,k Γ D O L,j,k K D O L,j,k
1,2 2.11 1.41 0.5836 12.1 1 + 10.5 X DOL , 2 0.89 1 + 4.65 X DOL , 2 1.67
1,3 1.19 1.00 0.0000 3.41 1 + 0.0702 X DOL , 1 0.90 1 + 0.967 X DOL , 3 1.92 1 + 0.0466 X DOL , 3 1.42
2,0 0.79 1.36 1.8532 8.86 1 0.0228 X DOL , 2 1.20
2,1 1.03 1.08 8.5081 3.30 1 + 0.0368 X DOL , 2 2.09 1 + 0.0943 X DOL , 1 1.43 1 + 3.86 X DOL , 1 0.76
3,1 0.64 1.00 0.0000 0.0601 1 + 0.0054 X DOL , 3 1.29 1 5.87 X DOL , 1 1.68 1 + 2.38 X DOL , 1 1.20