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Table 12 The PK parameters for Equation11modeling doxorubicinol for Moreira et al. [[28]] with paclitaxel present

From: A multi-compartment pharmacokinetic model of the interaction between paclitaxel and doxorubicin

j,k K D O L,j,k
1,2 15.9 1 + 14.0 X DOL , 2 0.50 1 + 8.04 X DOL , 2 1.24 1 + 7.23 X PTX , 1 0.66 1 + 0.0070 X PTX , 1 1.46 0.701 X PTX , 2 0.28 1 + 0.0005 X PTX , 2 6.85
1,3 4.82 1 + 0.0749 X DOL , 1 0.95 1 + 0.711 X DOL , 3 1.22 1 + 0.0433 X DOL , 3 1.26
2,0 13.8 1 0.0162 X DOL , 2 2.07 1 0.131 X PTX , 2 1.37 1 + 0.0004 X PTX , 2 6.68
2,1 5.03 1 + 0.0690 X DOL , 2 1.11 1 + 0.135 X DOL , 1 0.91 1 + 2.61 X DOL , 1 1.37 1 0.0434 X PTX , 1 1.10 1 + 0.0103 X PTX , 1 2.41 + 10.9 X PTX , 2 1.12 1 + 0.00007 X PTX , 2 6.94
3,1 0.0479 1 + 0.0047 X DOL , 3 1.10 1 7.87 X DOL , 1 1.45 1 + 2.33 X DOL , 1 1.22